171Impact of Rapid Bloodstream Pathogen Identification in Hospitalized Patients
نویسندگان
چکیده
171. Impact of Rapid Bloodstream Pathogen Identification in Hospitalized Patients Matthew Maslonka, MD; Alison G. Freifeld, MD; Mark E. Rupp, MD; Devon Greer, PharmD; Robbe Peetz, PA; Elizabeth Lyden, MS; Paul D. Fey, PhD; Trevor C. Van Schooneveld, MD; Division of Infectious Diseases, University of Nebraska Medical Center, Omaha, NE; Pharmacy and Nutrition, Nebraska Medical Center, Omaha, NE; College of Public Health, University of Nebraska Medical Center, Omaha, NE; Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
منابع مشابه
Duplex DNA-Invading γ-Modified Peptide Nucleic Acids Enable Rapid Identification of Bloodstream Infections in Whole Blood
UNLABELLED Bloodstream infections are a leading cause of morbidity and mortality. Early and targeted antimicrobial intervention is lifesaving, yet current diagnostic approaches fail to provide actionable information within a clinically viable time frame due to their reliance on blood culturing. Here, we present a novel pathogen identification (PID) platform that features the use of duplex DNA-i...
متن کاملID Learning Unit—Diagnostics Update: Current Laboratory Methods for Rapid Pathogen Identification in Patients With Bloodstream Infections
Diagnostic assays that rapidly identify bloodstream pathogens have the potential to improve patient outcomes and antibiotic stewardship efforts. Current tests are based on the detection of nucleic acids that are specific to a targeted pathogen or based on organism identification using mass spectrometry. Most rapid assays require a positive blood culture as their sample input and expedite pathog...
متن کاملProspective study of the performance of vibrational spectroscopies for rapid identification of bacterial and fungal pathogens recovered from blood cultures.
Rapid identification of microbial pathogens reduces infection-related morbidity and mortality of hospitalized patients. Raman spectra and Fourier transform infrared (IR) spectra constitute highly specific spectroscopic fingerprints of microorganisms by which they can be identified. Little biomass is required, so that spectra of microcolonies can be obtained. A prospective clinical study was car...
متن کاملMolecular Diagnosis and Characterization of Bacillus subtilis Isolated from Burn Wound in Iran
Background: Bacillus subtilis refers to stretched and sometimes curved, gram-positive, aerobic, and catalase-positive bacilli, which has thermo-resistant endospores. It has been known as a normal flora in the human but can be pathogens In the case of opportunistic. Also, it can be the pathogen of nosocomial infections such as wound among hospitalized patients. Purpose of this study was to ident...
متن کاملImproving the Diagnosis of Bloodstream Infections: PCR Coupled with Mass Spectrometry
The reference method for the diagnosis of bloodstream infections is blood culture followed by biochemical identification and antibiotic susceptibility testing of the isolated pathogen. This process requires 48 to 72 hours. The rapid administration of the most appropriate antimicrobial treatment is crucial for the survival of septic patients; therefore, a rapid method that enables diagnosis dire...
متن کامل